SPE Vacuum Manifolds, abbreviated as SPE, is a widely used. And popular sample pretreatment technology that uses solid adsorbents to adsorb target compounds in liquid samples, separate them from the sample matrix and interfering compounds, and then elute or heat desorption with eluent to achieve the purpose of separating and enriching target compounds. It is developed on the basis of traditional liquid-liquid extraction (LLE) using the principle of similar phase solubility based on the similarity between substances, and combining the basic knowledge of liquid chromatography (HPLC) and gas chromatography (GC) stationary phases that are currently widely used.
More introduction to SPE Vacuum Manifolds
In the process of solid-phase extraction, the attraction of the solid phase analyte is greater than that of the sample mother liquor. When the sample passes through the SPE column, the analyte is adsorbed on the solid surface. While other components pass through the column with the sample mother liquor. Finally, they are eluted with appropriate solvents. SPE itself can be divided into four types based on its principles: reverse SPE (RP-SPE), forward SPE (NP-SPE), ion exchange SPE (IE-SPE), and adsorption SPE (Absorption). In most cases, solid-phase extraction is applied to the treatment of liquid samples. To extract, concentrate, and purify volatile and semi volatile compounds in the samples. When it is necessary to use solid samples, the solid samples must be treated as liquid first.
SPE is mostly used to process liquid samples, extract, concentrate, and purify semi volatile and non volatile compounds. And can also be used for solid samples, but must first be processed into a liquid. At present, the main applications in China are the analysis of organic substances. Such as polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs) in water, pesticide. And herbicide residues in fruits, vegetables, and food, antibiotic analysis, and clinical drug analysis.It can be applied to various types of food safety testing, agricultural product residue monitoring. And pharmaceutical hygiene, environmental protection. And commodity inspection, tap water and chemical production laboratories.